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Open Access Article

International Journal of Obstetrics and Gynecology. 2022; 2: (2) ; 39-41 ; DOI: 10.12208/j.ijog.20220041.

Efficacy of low molecular weight heparin combined with low-dose aspirin in the treatment of early-onset severe preeclampsia
低分子量肝素联合小剂量阿司匹林治疗早发型重度子痫前期的疗效

作者: 张琼 *

临夏州人民医院 甘肃临夏

*通讯作者: 张琼,单位:临夏州人民医院 甘肃临夏;

发布时间: 2022-08-19 总浏览量: 330

摘要

目的 探讨低分子量肝素联合小剂量阿司匹林治疗早发型重度子痫前期的疗效。方法 选择我院2020年1月至2020年12月收治的100例早发型重度子痫前期患者,随机均分两组各50例,对照组采用常规治疗,研究组在此基础上联合低分子量肝素、小剂量阿司匹林治疗,对比效果。结果 治疗后研究组两组24小时尿量高于对照组,24小时尿蛋白定量低于对照组(P<0.05)。研究组不良妊娠结局发生率10.00%低于对照组30.00%(P<0.05)。结论 低分子量肝素、小剂量阿司匹林联合常规治疗子痫前期疗效显著。

关键词: 低分子量肝素;小剂量阿司匹林;早发型重度子痫前期;疗效

Abstract

Objective To investigate the efficacy of low molecular weight heparin combined with low-dose aspirin in the treatment of early-onset severe preeclampsia.
Methods 100 patients with early-onset severe pree- clampsia treated in our hospital from January 2020 to December 2020 were randomly divided into two groups with 50 cases in each group. The control group was treated with routine treatment, and the study group was treated with low molecular weight heparin and low-dose aspirin on this basis to compare the effects.
Results after treatment, the 24-hour urine volume of the two groups in the study group was higher than that of the control group, and the 24-hour urine protein quantity was lower than that of the control group (P<0.05). The incidence of adverse pre- gnancy outcomes in the study group was 10.00% lower than 30.00% in the control group (P<0.05).
Conclusion   low molecular weight heparin and low-dose aspirin combined with routine treatment of preeclampsia is effective.

Key words: Low molecular weight heparin; Low dose aspirin; Early onset severe preeclampsia; Curative effect

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引用本文

张琼, 低分子量肝素联合小剂量阿司匹林治疗早发型重度子痫前期的疗效[J]. 国际妇产科研究, 2022; 2: (2) : 39-41.