Open Access Article
International Journal of Obstetrics and Gynecology. 2022; 2: (2) ; 22-25 ; DOI: 10.12208/j.ijog.20220036.
Effect of daying -35 combined with metformin in the treatment of obesity polycystic ovary syndrome
达英-35联合二甲双胍治疗肥胖型多囊卵巢综合征的效果
作者:
范小华 *
镇江市妇幼保健院 江苏镇江
*通讯作者:
范小华,单位:镇江市妇幼保健院 江苏镇江;
发布时间: 2022-08-19 总浏览量: 545
PDF 全文下载
引用本文
收录截图(CNKI-Scholar)
万方数据(WANFANG DATA)
摘要
目的 探析达英-35联合二甲双胍治疗肥胖型多囊卵巢综合征的效果影响。方法 选取医院2021年2月~2022年2月所接收的60例肥胖型多囊卵巢综合征患者为研究对象,依照随机分配的原则,共分为对照组和研究组两组,每组各30例。对照组予以达英-35,研究组予以达英-35联合二甲双胍。观察并比较两组患者血清性激素、体质量指数、血脂、血糖、胰岛素指标情况以及两组患者临床治疗效果情况。结果 研究组患者LH、FSH、T、BMI、TC、TG、FBG、FINS等指标均明显优于对照组(P<0.05);研究组患者治疗效果的总有效率28例(93.33%)明显比对照组19(63.33%)高,差异具有统计学意义(P<0.05)。结论 达英-35联合二甲双胍在治疗肥胖型多囊卵巢综合征上的临床效果比较明显,可有效改善患者血清性激素指标以及血糖、血脂、胰岛素水平,有助于患者各项指标的改善,提高患者的恢复率,具有较高的临床应用价值。
关键词: 达英-35;二甲双胍;肥胖型;多囊卵巢综合征
Abstract
Objective To explore the effect of daying-35 combined with metformin in the treatment of obesity polycystic ovary syndrome. Methods A total of 60 patients with obese polycystic ovary syndrome received by our hospital from February 2021 to February 2022 were selected as the research objects. According to the principle of random allocation, they were divided into control group and study group, with 30 cases in each group. The control group was given tayin-35, and the study group was given tayin-35 combined with metformin. Obser- vation and comparison of serum sex hormone, body mass index, blood lipid, blood glucose, insulin and clinical treatment effect of two groups of patients. Results The indexes of LH, FSH, T, BMI, TC, TG, FBG and FINS in study group were significantly better than those in control group (P<0.05). The total effective rate of 28 patients (93.33%) in the study group was significantly higher than that in the control group 19 patients (63.33%), and the difference was statistically significant (P<0.05). Conclusion The clinical effect of daying -35 combined with metformin in the treatment of obese polycystic ovary syndrome is relatively obvious, which can effectively improve the serum sex hormone index, blood glucose, blood lipid and insulin levels of patients, contribute to the improvement of various indicators of patients, improve the recovery rate of patients, and has high clinical app- lication value.
Key words: Daying -35; Metformin; Fueling. Polycystic ovary syndrome
参考文献 References
[1]赵亚丽. 达英-35联合二甲双胍治疗肥胖型多囊卵巢综合征患者的疗效分析[J]. 临床研究,2021,29(8):95-97.
[2]夏雪怡,张川利. 达英-35联合二甲双胍治疗肥胖型多囊卵巢综合征疗效及对患者性激素水平、胰岛功能及脂肪因子的影响[J]. 陕西医学杂志,2018,47(8):1069-1071.
[3]刘素梅. 达英-35与二甲双胍联合治疗肥胖型多囊卵巢综合征对性激素及糖脂代谢影响[J]. 包头医学院学报,2017,33(12):29-31.
[4]仲子星,金碧辉. 达英-35与二甲双胍联合治疗肥胖型多囊卵巢综合征的疗效观察[J]. 中国现代医生,2018,56(25):71-73,78.
[5]汪旭虹,胡甜甜. 二甲双胍联合达英-35菊粉治疗肥胖型多囊卵巢综合征的效果及对患者血清相关指标的影响[J]. 中国妇幼保健,2020,35(22):4317-4320.
引用本文
范小华, 达英-35联合二甲双胍治疗肥胖型多囊卵巢综合征的效果[J]. 国际妇产科研究, 2022; 2: (2) : 22-25.