Comparison of clinical features and pregnancy outcomes of different chorionic twin pregnancies
不同绒毛膜性双胎妊娠临床特征比较及妊娠结局调查分析

摘要

目的 比较本院2016~2020年不同绒毛膜性双胎妊娠的临床特征及妊娠结局。方法 收集5年间分娩的孕妇数、双胎妊娠数、不同绒毛膜性双胎数、不同绒毛膜性的临床特征及妊娠结局等数据进行回顾性统计分析。结果 （1）2016~2020年孕妇分娩数42505例，双胎发生率1.24%；（2）双绒双羊占比66.79%高于单绒双羊的33.21%；（3）单绒双羊65.14%早产率高于双绒双羊47.16%（P＜0.01）；（4）妊娠期孕产妇主要8种并发症，单绒双羊发生率58.80%高于双绒双羊的50.57%，无统计学差异（P=0.072）；（5）早产低体重儿单绒双羊发生率44.29%高于双绒双羊31.68%，有统计学差异（P<0.01）。胎儿宫内发育受限前者16.29%高于后者12.64%，无统计学差异（P=0.107）；（6）新生儿窒息单绒双羊例发生率7.43%高于双绒双羊5.54%，但无统计学差异（P=0.230）；⑺缺陷儿单绒双羊发生率4.29%高于双绒双羊1.78%，有统计学差异（P=0.012）。结论 严格按照双胎妊娠诊治指南，对不同绒毛膜性双胎进行个体化规范化孕期诊疗，可将单绒双羊母儿并发症发生率降低至双绒双羊双胎水平。

Abstract

Objective To compare the clinical features and pregnancy outcomes of different chorionic twin pregnancies in our hospital from 2016 to 2020.
Methods The data of the number of pregnant women, the number of twin pregnancies, the number of different chorionic twins, the clinical characteristics and pregnancy outcomes of different chorionic types were collected for retrospective statistical analysis in 5 years.
Results (1) From 2016 to 2020, 42,505 pregnant women gave birth, and the incidence of twins was 1.24%; (2) the proportion of double-wool double sheep was 66.79%, which was higher than that of single-wool double-wool sheep, which was 33.21%; (3) single-wool double-wool double sheep was 65.14%. % preterm birth rate was 47.16% higher than that of double-wool double sheep (P<0.01); (4) There were 8 main complications of pregnant women during pregnancy, and the incidence rate of single-wool double sheep was 58.80% higher than that of double-wool double sheep, 50.57%, no statistics. (P=0.072); (5) The incidence rate of preterm low birth weight infants with single cashmere double sheep was 44.29% higher than that of double cashmere double sheep, 31.68%, with a statistical difference (P<0.01). Intrauterine growth restriction of the former was 16.29% higher than that of the latter, 12.64%, with no statistical difference (P=0.107). However, there was no statistical difference (P=0.230); (7) the incidence rate of single-wool double sheep in defective children was 4.29% higher than that of double-wool double sheep at 1.78%, with a statistical difference (P=0.012).
Conclusion   In strict accordance with the guidelines for the diagnosis and treatment of twin pregnancy, individualized and standardized pregnancy diagnosis and treatment of different chorionic twins can reduce the incidence of complications of monochorionic twins to the level of dichorionic twins.