摘要
目的 在接受体外受精-胚胎移植（IVF-ET）术后发生重度卵巢过度刺激综合征（OHSS）并发胸腹腔积液的患者中，探讨有效的治疗方法。方法 病例筛选2021年1月至2023年1月期间来我院的患者60例，按照并发症的早中晚三个分期将其分成甲组、乙组和丙组，甲组采取万汶进行治疗、乙组采取清蛋白联合万汶进行治疗，丙组采取早期胸腹腔抽吸的系列措施进行治疗，对三组结果进行对比。结果 在肌酐水平上，治疗后甲乙丙三组的数据均显著优于治疗前，对比差异显著（P<0.05）；治疗后，在清蛋白和总蛋白水平上，乙组的相应数据均优于甲组和丙组，对比差异显著（P<0.05）；在住院时间和治疗费用上，观察组的药物流产成功率和对照组之间差别较小，对比差异不显著（P>0.05）。结论 在IVF-ET术后发生（OHSS）并发胸腹腔积液患者中，应当对其展开积极的胸腹腔积液抽吸措施，并根据患者的恢复情况来采取扩容治疗，这种治疗方法不仅可以改善并发症，患者的住院时间和治疗费用都大大减少。
关键词： IVF-ET；OHSS；胸腹腔积液；临床疗效
Abstract
Objective To investigate the effective treatment of severe ovarian hyperstimulation syndrome (OHSS) complicated by pleuroperitoneal effusion after in vitro fertilization-embryo transfer (IVF-ET). Methods Sixty patients who came to our hospital from January 2021 to January 2023 were divided into group A, Group B and group C according to three stages of early, middle and late complications. Group A was treated with Wanwen, group B was treated with albumin combined with Wanwen, and group C was treated with a series of measures of early chest and abdominal suction. The results of the three groups were compared. Results In creatinine level, the data of group A, B and C after treatment were significantly better than before treatment, and the difference was significant (P<0.05); After treatment, the corresponding data of albumin and total protein levels in group B were better than those in group A and group C, and the difference was significant (P<0.05). In terms of hospital stay and treatment cost, there was little difference in the success rate of medical abortion between the observation group and the control group, and the comparison difference was not significant (P>0.05). Conclusion In patients with pleuroceliac effusion after OHSS of IVF-ET, active pleuroceliac effusion should be aspirated, and dilatation therapy should be taken according to the patients' recovery. This treatment method can not only improve the complications, but also greatly reduce the patient's hospital stay and treatment costs.
Key words： IVF-ET; OHSS; Pleuroperitoneal fluid; Clinical effect
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