Clinical study of acupuncture and metformin in the treatment of obese polycystic ovarian syndrome
针刺配合耳穴压豆联合二甲双胍治疗肥胖型多囊卵巢综合征的临床研究

摘要

目的 分析针刺、耳穴压豆和二甲双胍联合用于肥胖型多囊卵巢综合征的价值。方法 对2018年1月—2021年12月扬州大学建湖临床医学院接诊肥胖型多囊卵巢综合征病人（n=64）进行随机分组，试验和对照组各32人，前者采取针刺、耳穴压豆和二甲双胍联合疗法，后者采用二甲双胍。对比FSH等指标。结果 关于FSH、LH、T和E2，在疗程结束时：试验组的数据比对照组低（P＜0.05）。关于总有效率，试验组数据96.88%，和对照组75.0%相比更高（P＜0.05）。关于空腹胰岛素和空腹血糖，在疗程结束时：试验组的数据分别是（130.25±4.96）pmol/L、（5.04±0.26）mmol/L，和对照组（137.49±5.23）pmol/L、（5.41±0.34）mmol/L相比更低（P＜0.05）。关于妊娠成功率，试验组数据53.13%，和对照组28.13%相比更高（P＜0.05）。结论 肥胖型多囊卵巢综合征联用针刺、耳穴压豆与二甲双胍，疗效显著，性激素水平改善更加明显，空腹胰岛素与空腹血糖降低更为迅速，妊娠成功率也更高。

Abstract

Objective: To analyze the value of acupuncture, ear point pressure beans and metformin combined use in obese polycystic ovary syndrome.
Methods: Patients with obese polycystic ovary syndrome (n=64) from January 2018 to December 2021 were randomized. 32 patients in the control group were combined with acupuncture, ear point pressure beans and metformin, while the latter used metformin. Compared with FSH and other indicators.
Results: For FSH, LH, T, and E2, at the end of the session: the test group was lower than the control group (P <0.05). Regarding the total response rate, the test group data was 96.88%, which was higher than the 75.0% in the control group (P <0.05). For fasting insulin and fasting glucose, at the end of the session: the data were (130.25 ± 4.96) pmol/L, (5.04 ± 0.26) mmol/L, and pmol/L (137.49 ± 5.43) (P <0.0.34) mmol/L, respectively. Regarding the pregnancy success rate, the test group data was 53.13%, which was higher than the 28.13% in the control group (P <0.05).
Conclusion  : The combination of acupuncture, ear pressure and metformin showed significant improvement of sex hormone levels, faster reduction of fasting insulin and fasting blood glucose, and higher success rate of pregnancy.