To explore the clinical effect of mifepristone combined with methotrexate in the conservative treatment of ectopic pregnancy
探究在宫外孕保守治疗中应用米非司酮与甲氨蝶呤联合方案的临床效果

摘要

目的 针对米非司酮与甲氨蝶呤联合保守治疗宫外孕的效果展开分析。方法 选取2015年1月至2022年2月收治的宫外孕患者40例，随机分为观察组20例，对照组20例，对照组利用甲氨蝶呤治疗，观察组采取甲氨蝶呤联合米非司酮治疗，对比效果。结果 观察组临床症状消失时间低于对照组(P<0.05)；观察组血清指标低于对照组(P<0.05)；两组不良反应发生率组间对比(P>0.05)；观察组有效率高于对照组(P<0.05)。结论 宫外孕保守治疗患者采取甲氨蝶呤联合米非司酮治疗可快速改善临床症状，降低血清指标，且不良反应较少。

Abstract

Objective: to analyze the effect of mifepristone combined with methotrexate in the conservative treatment of ectopic pregnancy.
Methods: 40 patients with ectopic pregnancy admitted from January 2015 to February 2022 were randomly divided into the observation group (20 cases) and the control group (20 cases). The control group was treated with methotrexate and the observation group was treated with methotrexate and mifepristone. The effects were compared.
Results: the disappearance time of clinical symptoms in the observation group was lower than that in the control group (P<0.05); The serum indexes in the observation group were lower than those in the control group (P<0.05); The incidence of adverse reactions between the two groups was compared (P>0.05); The effective rate of the observation group was higher than that of the control group (P<0.05).
Conclusion  : the combination of methotrexate and mifepristone can improve the clinical symptoms and reduce the serum level of patients with ectopic pregnancy, with less adverse reactions.